Kullanım Talimatı
Each tablet contains: 400mg of Albendazol.
Albendazol is considered as a wide spectrum anthelmintic, which affects on a large group of intestinal worms.
The Biological half life of it is 8.5 hours.
The maximum plasma concentration of Albendazol reaches to: 0.20mg/L after one daily dose of 400mg.
The mechanism of effectiveness is unknown but it is sure scientifically that Albendazol as derivative of Benzaimidazol has a mechanism of effectiveness depends on minimize of the ability of parasite to absorption and beneficiary of glucose which is available in the intestine of host, and that is caused disorders in synthesis of the ATP which is parasites energy source, so that the parasite will die, especially if the parasite is in a growing phase in which the need of power is very great. After parasite die, it will be expelled with stool during three days at maximum.
The Biological half life of it is 8.5 hours.
The maximum plasma concentration of Albendazol reaches to: 0.20mg/L after one daily dose of 400mg.
The mechanism of effectiveness is unknown but it is sure scientifically that Albendazol as derivative of Benzaimidazol has a mechanism of effectiveness depends on minimize of the ability of parasite to absorption and beneficiary of glucose which is available in the intestine of host, and that is caused disorders in synthesis of the ATP which is parasites energy source, so that the parasite will die, especially if the parasite is in a growing phase in which the need of power is very great. After parasite die, it will be expelled with stool during three days at maximum.
Clinical studies are done to investigate the effect of Parazol on the various parasites, and these studies prove that Parazol is useful as killer according to the following rate:
1 -100% of: Ascaris lumbricoides - Ankylostoma duodenale - Filaire - Trichocephale - Strengyloidos stercoralis - Giardia lamblia.
2-86% of: Cestodes - Taenia saginata - Taenia solium.
3-66% of: Hymenolepis nana.
4-90% of: Trematodes.
Also Parazol is effective against many worms such as Oxyuris and others.
1 -100% of: Ascaris lumbricoides - Ankylostoma duodenale - Filaire - Trichocephale - Strengyloidos stercoralis - Giardia lamblia.
2-86% of: Cestodes - Taenia saginata - Taenia solium.
3-66% of: Hymenolepis nana.
4-90% of: Trematodes.
Also Parazol is effective against many worms such as Oxyuris and others.
1-Pregnancy and lactation, it is not recommended using Parazol during pregnancy and lactation period, the clinical trials on animals proved that main metabolite of Albendazol is Albendazol sulfoxid which is excreted with the milk of the mother.
2-It is not recommended to use Parazol for children under the age of 6 years.
2-It is not recommended to use Parazol for children under the age of 6 years.
It is only appeared in the high doses and in the long term treatment, these symptoms are intestinal symptoms - headache - fever - dermatological sensitive reactions (itching - urticaria) disorders in the hemogram - lossing hair, high levels of hepatic enzymes.
The treatment of parasites like (Trichocephale, Strengyloidos stercoralis, Ascaris lumbricoides) oxyuries and other slight infections,-the daily dose contains two tablets, one tab. In the morning and one tab. In the evening during having food with little liquids and for a period of (3 – 6) days, and it is preferable to repeat the treatment after 3 weeks.
The treatment of cestodes and ankylostmiase, it is recommended to take the dose two times daily for 28 days followed by 14 days as a rest then repeating the treatment again, it is not recommended to repeat the treatment more than three times strictly.
The treatment of cestodes and ankylostmiase, it is recommended to take the dose two times daily for 28 days followed by 14 days as a rest then repeating the treatment again, it is not recommended to repeat the treatment more than three times strictly.
Parazol causes confusion in the efficacy of Insulin.
The absorption of Parazol will be increased when the treatment is accompanied with rich fatty food.
A Blister contains 10 tablets with yellowish white colour, has a lable in a colored carton pack.